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Mouse PROM1 Recombinant Protein (N-GST & C-His)
Key Features

Mouse PROM1 Recombinant Protein (N-GST & C-His) (GXRP14001)

SKU GXRP14001
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-GST & C-His
€347 - €1,827

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Description

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Mouse PROM1 Recombinant Protein (N-GST & C-His)

Mouse PROM1 Recombinant Protein (N-GST & C-His) is a recombinant protein expressed in E. coli, spanning Gly50-Cys140, with an N-terminal GST tag and a C-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Prominin-1 is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. For research use only.

Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

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