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Mouse RNF43 Recombinant Protein (N-His)
Key Features

Mouse RNF43 Recombinant Protein (N-His) (GXRP06546)

SKU GXRP06546
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Mouse RNF43 Recombinant Protein (N-His)

Mouse RNF43 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln44-Lys189, with an N-terminal His tag. Predicted molecular weight: 18.34 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein ligase RNF43 is a ~86 kDa protein. E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. For research use only.

Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification.

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