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Mouse S100A10 Recombinant Protein (RPPB4547)

SKU:
RPPB4547
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
P08207
€273
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Description

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Product Name:Mouse S100A10 Recombinant Protein
Product Code:RPPB4547
Size:10µg
Species:Mouse
Target:S100A10
Synonyms:ProteinS100-A10, Calpactin I light chain, Calpactin-1 light chain, Cellular ligand of,annexin II, S100 calcium-binding protein A10, p10 protein, p11, S100a10, Cal1l.
Source:Escherichia Coli
Physical Appearance:Sterilefiltered colorless solution.
Formulation:S100A10protein solution (1mg/ml) containing phosphate buffered saline (pH 7.4) and 10%glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greaterthan 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHHSSGLVPRGSH MGSMPSQMEH AMETMMLTFH RFAGDKDHLT KEDLRVLMER EFPGFLENQKDPLAVDKIMK DLDQCRDGKV GFQSFLSLVA GLTIACNDYF VVNMKQKGKK

S100A10 is a member of the S100 family of proteins contains two EF-hand calcium-binding motifs and is thought to be involved in the regulation of a number of cellular processes including cell cycle progression and differentiation. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. S100A10 may function in exocytosis and endocytosis.

S100A10 MouseRecombinant produced in E. coli is a single, non-glycosylated polypeptide chaincontaining 120 amino acids (1-97a.a) and having a molecular mass of 13.6kDa.S100A10 isfused to a 23 amino acid His-tag at N-terminus & purified by proprietarychromatographic techniques.

UniProt Protein Function:S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family.
UniProt Protein Details:

Protein type:Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extrinsic to plasma membrane; lipid raft

Molecular Function:protein binding; protein homodimerization activity; calcium ion binding; lipid binding

Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding

NCBI Summary:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]
UniProt Code:P08207
NCBI GenInfo Identifier:46397706
NCBI Gene ID:6281
NCBI Accession:P60903.2
UniProt Secondary Accession:P08207,P08207,
UniProt Related Accession:P60903
Molecular Weight:11kDa
NCBI Full Name:Protein S100-A10
NCBI Synonym Full Names:S100 calcium binding protein A10
NCBI Official Symbol:S100A10��
NCBI Official Synonym Symbols:42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG��
NCBI Protein Information:protein S100-A10
UniProt Protein Name:Protein S100-A10
UniProt Synonym Protein Names:Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Protein Family:Protein
UniProt Gene Name:S100A10��
UniProt Entry Name:S10AA_HUMAN

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