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Mouse SEMA4A Recombinant Protein (N-His)
Key Features

Mouse SEMA4A Recombinant Protein (N-His) (GXRP10520)

SKU GXRP10520
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse SEMA4A Recombinant Protein (N-His)

Mouse SEMA4A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg41-Cys546, with an N-terminal His tag. Predicted molecular weight: 58.47 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Semaphorin-4A is a ~83 kDa protein. Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. For research use only.

Regulates glutamatergic and GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2.

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