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Mouse SIGLEC12 Recombinant Protein (N-His)
Key Features

Mouse SIGLEC12 Recombinant Protein (N-His) (GXRP08033)

SKU GXRP08033
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Mouse SIGLEC12 Recombinant Protein (N-His)

Mouse SIGLEC12 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln19-Ala253, with an N-terminal His tag. Predicted molecular weight: 28.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sialic acid-binding Ig-like lectin 12 (SIGLEC12) is a ~51 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. For research use only.

The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

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