Description
Mouse SORT1 Recombinant Protein (N-His)
Mouse SORT1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr98-Val600, with an N-terminal His tag. Predicted molecular weight: 57.97 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sortilin is a ~91 kDa protein. Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. For research use only.
Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. Also required for protein transport from the Golgi apparatus to the endosomes.
| Product Name: | Mouse SORT1 Recombinant Protein (N-His) |
| SKU: | GXRP08850 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Sortilin, Neurotensin receptor 3, NTR3, mNTR3, Sort1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr98-Val600 |
| Calculated MW: | 57.97 kDa |
| UniProt: | Q6PHU5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
