Description
Mouse TENT4B Recombinant Protein (N-His)
Mouse TENT4B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe2-Arg633, with an N-terminal His tag. Predicted molecular weight: 70.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Terminal nucleotidyltransferase 4B (TENT4B) is a ~69 kDa protein. Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. For research use only.
Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs.
| Product Name: | Mouse TENT4B Recombinant Protein (N-His) |
| SKU: | GXRP08002 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Terminal nucleotidyltransferase 4B, Non-canonical poly(A) RNA polymerase PAPD5, 2.7.7.19, PAP-associated domain-containing protein 5, Terminal guanylyltransferase, 2.7.7.-, Terminal uridylyltransferase 3, TUTase 3, Topoisomerase-related function protein 4-2, TRF4-2, Tent4b, Papd5 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe2-Arg633 |
| Calculated MW: | 70.81 kDa |
| UniProt: | Q68ED3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
