Description
Mouse TIMP1 Recombinant Protein (N-His)
Mouse TIMP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning His31-Arg205, with an N-terminal His tag. Predicted molecular weight: 21.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Metalloproteinase inhibitor 1 (TIMP1) is a ~22 kDa protein. Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. For research use only.
Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
| Product Name: | Mouse TIMP1 Recombinant Protein (N-His) |
| SKU: | GXRP06483 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Erythroid-potentiating activity, TIMP, EPA, TIMP1, Metalloproteinase inhibitor 1, TIMP-1, Fibroblast collagenase inhibitor, Collagenase inhibitor, CLGI, Tissue inhibitor of metalloproteinases 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | His31-Arg205 |
| Calculated MW: | 21.98 kDa |
| UniProt: | P12032 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
