Description
Mouse TRADD Recombinant Protein (N-His)
Mouse TRADD Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Trp11-Gln142, with an N-terminal His tag. Predicted molecular weight: 17.09 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tumor necrosis factor receptor type 1-associated DEATH domain protein is a ~34 kDa protein. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. For research use only.
Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.
| Product Name: | Mouse TRADD Recombinant Protein (N-His) |
| SKU: | GXRP12079 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TRADD, Tumor necrosis factor receptor type 1-associated DEATH domain protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Trp11-Gln142 |
| Calculated MW: | 17.09 kDa |
| UniProt: | Q3U0V2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
