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Mouse TRPV1 Recombinant Protein (N-His)
Key Features

Mouse TRPV1 Recombinant Protein (N-His) (GXRP07835)

SKU GXRP07835
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse TRPV1 Recombinant Protein (N-His)

Mouse TRPV1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg115-Arg433, with an N-terminal His tag. Predicted molecular weight: 38.01 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a ~94 kDa protein. Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. For research use only.

Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius.

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