The Mannose Receptor/CD206 Polyclonal Antibody (CAB8301) is a high-quality antibody developed for reliable detection and analysis of target proteins. This cell surface receptor plays a crucial role in the immune system, specifically in the recognition and clearance of pathogens and foreign molecules. Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in Western blot applications. It binds to the MRC1 protein, enabling researchers to detect and analyze its expression in various cell types. This makes it an ideal tool for studies in immunology, infectious diseases, and cancer research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
Mannose Receptor/CD206 Polyclonal Antibody
SKU:
CAB8301
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Cell Membrane, Endosome Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
166kDa
Observed MW:
190-250kDa
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Purification Method
Affinity purification
Gene ID
4360
RRID
AB_2770422
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Mannose Receptor/CD206 Rabbit pAb (CAB8301) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): Jurkat. Exposure time: 30s.
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