UniProt Protein Function: | MTHFD2L: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.5.1.15; EC 3.5.4.9; Hydrolase; Mitochondrial; OxidoreductaseChromosomal Location of Human Ortholog: 4q13.3Cellular Component: cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrionMolecular Function: methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; methylenetetrahydrofolate dehydrogenase (NADP+) activityBiological Process: 10-formyltetrahydrofolate metabolic process; folic acid metabolic process; histidine biosynthetic process; methionine biosynthetic process; one-carbon metabolic process; purine nucleotide biosynthetic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9H903 |
NCBI GenInfo Identifier: | 222418558 |
NCBI Gene ID: | 441024 |
NCBI Accession: | NP_001138450.1 |
UniProt Secondary Accession: | Q9H903,Q6P079, Q8N560 |
UniProt Related Accession: | Q9H903 |
Molecular Weight: | 32,891 Da |
NCBI Full Name: | probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform 2 |
NCBI Synonym Full Names: | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like |
NCBI Official Symbol: | MTHFD2LÂ Â |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 |
UniProt Protein Name: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 |
UniProt Synonym Protein Names: | NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; MTHFD2-like |
Protein Family: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase |
UniProt Gene Name: | MTHFD2LÂ Â |
UniProt Entry Name: | |