MUC3A Antibody (PACO18715)
- SKU:
- PACO18715
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | MUC3A Antibody (PACO18715) |
| Antibody SKU: | PACO18715 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human MUC3A |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18715(MUC3A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18715(MUC3A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation. |
| Synonyms: | mucin 3A, cell surface associated |
| UniProt Protein Function: | MUC3A: Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7q22Cellular Component: Golgi lumen; extracellular region; integral to membraneMolecular Function: extracellular matrix structural constituent; extracellular matrix constituent, lubricant activityBiological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modificationDisease: Inflammatory Bowel Disease 11 |
| UniProt Protein Details: | |
| NCBI Summary: | The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008] |
| UniProt Code: | Q02505 |
| NCBI GenInfo Identifier: | 126302571 |
| NCBI Gene ID: | |
| NCBI Accession: | Q02505.2 |
| UniProt Secondary Accession: | Q02505,O14650, O14651, O43418, O43421, Q02506, Q6W763 Q9H3Q7, Q9UKW9, Q9UN93 |
| UniProt Related Accession: | Q02505 |
| Molecular Weight: | 43.7kDa |
| NCBI Full Name: | Mucin-3A |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Mucin-3A |
| UniProt Synonym Protein Names: | Intestinal mucin-3A |
| Protein Family: | |
| UniProt Gene Name: | MUC3AÂ Â |
| UniProt Entry Name: | MUC3A_HUMAN |
| ELISA Kits |
| Human Mucin-3A (MUC3A) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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