The MYO1B Monoclonal Antibody is a high-quality research tool designed for investigating the function of MYO1B, a myosin motor protein involved in various cellular processes such as membrane trafficking, cell movement, and mechanotransduction. This specific monoclonal antibody, generated in mice, exhibits strong reactivity with human MYO1B protein and is suitable for use in Western blot and immunofluorescence applications.MYO1B is known to play a critical role in cell motility, actin cytoskeleton organization, and lipid droplet dynamics.
Dysregulation of MYO1B has been implicated in various diseases including cancer, neurological disorders, and metabolic syndromes. By targeting MYO1B with this monoclonal antibody, researchers can gain valuable insights into the cellular functions and molecular mechanisms associated with MYO1B, paving the way for potential therapeutic interventions in disease contexts related to MYO1B dysregulation.
Product Name:
MYO1B Monoclonal Antibody
SKU:
CAB21113
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 916-1136 of Human MYO1B (NP_001123630.1).
actin cytoskeleton, cytoplasm, early endosome, extracellular exosome, filopodium, perinuclear region of cytoplasm, plasma membrane
Calculated MW:
132kDa
Observed MW:
132kDa
Enables ATP binding activity; actin filament binding activity; and microfilament motor activity. Involved in actin filament organization and post-Golgi vesicle-mediated transport. Located in several cellular components, including actin filament; endosome; and perinuclear region of cytoplasm. Colocalizes with trans-Golgi network membrane.
Purification Method:
Affinity purification
Gene ID:
4430
Clone Number:
ARC2990
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using MYO1B Rabbit mAb (CAB21113) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
