The NSUN7 Antibody (PAC03822) is a valuable tool for research involving NSUN7, a protein involved in RNA methylation and modification. This polyclonal antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. It binds specifically to the NSUN7 protein, allowing for precise detection and analysis in various cell types.NSUN7 is known to play a crucial role in regulating RNA methylation, a process that is essential for proper gene expression and cellular function.
Dysregulation of NSUN7 has been linked to various diseases such as cancer and neurodevelopmental disorders, making it a promising target for therapeutic interventions. The NSUN7 Antibody is a valuable tool for researchers studying RNA modifications and their implications in disease states.
Antibody Name:
NSUN7 Antibody (PACO38322)
Antibody SKU:
PACO38322
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Putative methyltransferase NSUN7 protein (1-300AA)
Immunohistochemistry of paraffin-embedded human testis tissue using PACO38322 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO38322 at dilution of 1:100.
Background:
May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
Synonyms:
Putative methyltransferase NSUN7 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 7), NSUN7
UniProt Protein Function:
NSUN7: May have S-adenosyl-L-methionine-dependent methyl- transferase activity. Belongs to the methyltransferase superfamily. RsmB/NOP family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Methyltransferase; EC 2.1.1.-Chromosomal Location of Human Ortholog: 4p14Molecular Function: methyltransferase activity; RNA bindingBiological Process: methylation; sperm mitochondrion organization and biogenesis; sperm motility
