| UniProt Protein Function: | ONECUT2: Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B. Belongs to the CUT homeobox family.Protein type: Cell development/differentiation; DNA-binding; Transcription factor; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 18q21.31Cellular Component: actin cytoskeleton; nucleoplasm; nucleusBiological Process: cell differentiation; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95948 |
| NCBI GenInfo Identifier: | 294862454 |
| NCBI Gene ID: | 9480 |
| NCBI Accession: | O95948.2 |
| UniProt Secondary Accession: | O95948 |
| UniProt Related Accession: | O95948 |
| Molecular Weight: | 54,303 Da |
| NCBI Full Name: | One cut domain family member 2 |
| NCBI Synonym Full Names: | one cut homeobox 2 |
| NCBI Official Symbol: | ONECUT2Â Â |
| NCBI Official Synonym Symbols: | OC2; OC-2Â Â |
| NCBI Protein Information: | one cut domain family member 2 |
| UniProt Protein Name: | One cut domain family member 2 |
| UniProt Synonym Protein Names: | Hepatocyte nuclear factor 6-beta; HNF-6-beta; One cut homeobox 2; Transcription factor ONECUT-2; OC-2 |
| Protein Family: | One cut domain family |
| UniProt Gene Name: | ONECUT2Â Â |
| UniProt Entry Name: | ONEC2_HUMAN |
