Onfekafusp Alfa (Research-Grade) is a research-grade biosimilar monoclonal antibody targeting EDB. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research. • EDB-FN targeted probes for the surgical navigation, radionuclide imaging, and therapy of thyroid cancer., PMID:36807768 • EDB-FN Targeted Peptide-Drug Conjugates for Use against Prostate Cancer., PMID:31277465 • EDB-FN-targeted probes for near infrared fluorescent imaging and positron emission tomography imaging of breast cancer in mice., PMID:39333775 • Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade., PMID:35793468 • Evaluation of EDB Fibronectin in Plasma, Patient-Derived Xenograft Formalin-Fixed Paraffin-Embedded and Fresh Frozen Tumor Tissues Using Immunoaffinity LC-MS/MS., PMID:36049057 • EDB Fibronectin-Specific SPECT Probe 99m Tc-HYNIC-ZD2 for Breast Cancer Detection., PMID:30023665 • Tenascin-C: Form versus function., PMID:25482829 • EDB Fibronectin Specific Peptide for Prostate Cancer Targeting., PMID:25848940 • EDB fibronectin and angiogenesis -- a novel mechanistic pathway., PMID:16308732 • RT-PCR detection of fibronectin EDA+ and EDB+ mRNA isoforms: molecular markers for hepatocellular carcinoma., PMID:7509777
Human alkaline phosphatase, tissue-nonspecific isozyme/AP-TNAP soluble fragment fused to a human immunoglobulin G4 heavy chain constant region fragment fused to a deca-aspartate peptide, disulfide bridged dimer.
