The OR52E2 Monoclonal Antibody (PACO02439) is a valuable tool for researchers studying OR52E2, a member of the olfactory receptor family involved in detecting odor molecules. This antibody, produced through hybridoma technology, exhibits high specificity and sensitivity for detecting OR52E2 in various experimental settings. It is validated for use in immunohistochemistry and immunofluorescence applications, allowing for precise visualization and localization of OR52E2 within tissues or cells.OR52E2, also referred to as a chemosensory receptor, plays a crucial role in the olfactory system by detecting specific odor molecules and initiating the olfactory signal transduction pathway.
Understanding the function and expression patterns of OR52E2 is essential for unraveling the complexities of odor perception and discrimination. This antibody provides researchers with a reliable tool for investigating the physiological roles of OR52E2 in the context of sensory perception and olfactory processing.
Antibody Name:
OR52E2 Antibody
Antibody SKU:
PACO02439
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 52E2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
OR52E2; Olfactory receptor 52E2
UniProt Protein Function:
OR52E2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-passChromosomal Location of Human Ortholog: 11p15.4Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
