ORF3 Antibody (PACO35150)
- SKU:
- PACO35150
- Product Type:
- Antibody
- Reactivity:
- Virus - Hepatitis E
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | ORF3 Antibody (PACO35150) |
| Antibody SKU: | PACO35150 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Hepatitis E virus genotype 1 |
| Immunogen: | Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways. |
| Synonyms: | Protein ORF3 (pORF3), ORF3 |
| UniProt Protein Function: | May act as a viral regulatory protein involved in the modulation of mitogenic signaling pathways. May be involved in virion morphogenesis and viral pathogenesis. Expedites the processing and secretion of AMBP from the hepatocyte. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O90299 |
| NCBI GenInfo Identifier: | 189036527 |
| NCBI Gene ID: | |
| NCBI Accession: | O90299.2 |
| UniProt Secondary Accession: | O90299,Q68984 |
| UniProt Related Accession: | O90299 |
| Molecular Weight: | 27.8kD |
| NCBI Full Name: | Protein ORF3 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Protein ORF3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein |
| UniProt Gene Name: | ORF3Â Â |
| UniProt Entry Name: |