Purinergic Receptor P2Y6 Rabbit Polyclonal Antibody (CAB2485)
- SKU:
- CAB2485
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | Purinergic Receptor P2Y6 Rabbit Polyclonal Antibody |
SKU: | CAB2485 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Purinergic Receptor P2Y6 (NP_789766.1). |
Sequence: | GFLL PFAA LLAC YCLL ACRL CRQD GPAE PVAQ ERRG KAAR MAVV VAAA FAIS FLPF HITK TAYL AVRS TPGV PCTV LEAF AAAY KGTR PFAS ANSV LDPI L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | P2Y6; Purinergic Receptor P2Y6 |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 36kDa |
Observed MW: | 42kDa |
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method: | Affinity purification |
Gene ID: | 5031 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |