Pamrevlumab Antibody is a research-grade biosimilar monoclonal antibody targeting IGFBP8. It is a human IgG1-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.
CCN family member 2 (IGFBP8,IGF-binding protein 8,IBP-8,CTGF,HCS24,CCN family member 2,CCN2,Cellular communication network factor 2,Hypertrophic chondrocyte-specific protein 24,Connective tissue growth factor,Insulin-like growth factor-binding protein 8,IGFBP-8) is a ~38 kDa protein. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Product Name:
Pamrevlumab Antibody
SKU:
GXBS00054
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
IGFBP8
Isotype:
IgG1-kappa
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
FG-3019, 946415-13-0
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
