The PARK7 Monoclonal Antibody (CAB19097) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it an invaluable asset for studies in Parkinson's disease, cancer, and other conditions where Park7 is implicated.Park7, a multifunctional protein involved in oxidative stress response and cell survival pathways, has been linked to neurodegenerative disorders like Parkinson's disease. The Park7 Rabbit Monoclonal Antibody binds specifically to the Park7 protein, enabling precise detection and analysis in various experimental settings, including Western blot applications.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PARK7 Monoclonal Antibody
SKU:
CAB19097
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0354
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Purification Method
Affinity purification
Gene ID
11315
RRID
AB_2862589
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using DJ-1/PARK7 Rabbit mAb (CAB19097) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Immunohistochemistry analysis of paraffin-embedded Rat testis tissue using DJ-1/PARK7 Rabbit mAb (CAB19097) at a dilution of 1:200 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Buffer (pH 6.0) prior to IHC staining.
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