The Pax7 Rabbit Monoclonal Antibody (CAB4134) is a cutting-edge tool for researchers studying Pax7, a transcription factor critical for skeletal muscle development and regeneration. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards Pax7 in human samples, making it an ideal choice for applications such as immunofluorescence and immunohistochemistry.Pax7 is a key regulator of muscle stem cells, known as satellite cells, and is essential for the maintenance and repair of skeletal muscle tissue. Dysregulation of Pax7 has been implicated in muscle diseases and disorders, making it a vital target for investigation in the fields of muscle biology and regenerative medicine.
By using the Pax7 Rabbit Monoclonal Antibody, researchers can accurately detect and analyze Pax7 expression in various experimental settings, providing valuable insights into the role of this transcription factor in muscle development, regeneration, and disease. This antibody is a valuable tool for advancing our understanding of Pax7 biology and its potential applications in the development of novel therapies for muscle-related conditions.
Product Name:
PAX7 Rabbit Monoclonal Antibody
SKU:
CAB4134
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PAX7 (P23759).
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5081
Clone Number:
ARC0914
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PAX7 Rabbit mAb (CAB4134) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
