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PCNA Monoclonal Antibody (MACO0656)

SKU:
MACO0656
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ELISA
Conjugation:
Unconjugated
Isotype:
IgG1
Host Species:
Mouse
€249
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Description

Product Name:PCNA Monoclonal Antibody
Product Code:MACO0656
Size: 50µg
Target Names:PCNA
Species Reactivity:N/A
Host Species:Mouse
Antigen Species:N/A
Tested Applications:ELISA
Isotype:IgG1
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Monoclonal
Antigen:PCNA fusion protein
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:Protein G purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Cyclin, PCNA
Uniprot ID:N/A
Background:Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution; the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells. This antibody is a rabbit polyclonal antibody raised against an internal region of human PCNA.
Research Area:Others

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