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PCNA Rabbit Polyclonal Antibody (CAB13336)

SKU:
CAB13336
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-PCNA Antibody CAB13336
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-PCNA Antibody CAB13336
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-PCNA Antibody CAB13336
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-PCNA Antibody CAB13336
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PCNA Rabbit Polyclonal Antibody
SKU:CAB13336
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 162-261 of human PCNA (NP_002583.1).
Sequence:CAKD GVKF SASG ELGN GNIK LSQT SNVD KEEE AVTI EMNE PVQL TFAL RYLN FFTK ATPL SSTV TLSM SADV PLVV EYKI ADMG HLKY YLAP KIED EEGS
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:ATLD2; PCNA
Positive Sample:HeLa,MCF7,293T,C2C12,COS-7,Rat testis
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:29kDa
Observed MW:34kDa

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Purification Method:Affinity purification
Gene ID:5111
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PCNA Rabbit pAb (CAB13336) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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