Description
PCOLCE2 Antibody (PACO28838)
The PCOLCE2 Polyclonal Antibody (PACO28838) is a valuable tool for researchers studying the PCOLCE2 protein, which plays a role in various biological processes such as fibrinolysis and extracellular matrix remodeling. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for use in Western blot applications.PCOLCE2, also known as procollagen C-endopeptidase enhancer 2, is involved in the activation of the metalloproteinase procollagen C-endopeptidase enhancer 1 (PCOLCE1), which is essential for collagen metabolism and wound healing.
The precise functions of PCOLCE2 make it an exciting target for research in areas such as tissue remodeling, fibrosis, and cardiovascular disease.By utilizing the PCOLCE2 Polyclonal Antibody, researchers can gain valuable insights into the expression and activity of PCOLCE2 in various cell types and tissues, providing a deeper understanding of its role in physiological and pathological conditions. This antibody is a valuable tool for studies aimed at unraveling the complex mechanisms involving PCOLCE2 and its potential implications for therapeutic interventions.
| Antibody Name: | PCOLCE2 Antibody (PACO28838) |
| Antibody SKU: | PACO28838 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Procollagen C-endopeptidase enhancer 2 protein (24-415AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: PCOLCE2 antibody at 8µg/ml Lane 1: MCF-7 whole cell lysate Lane 2: A549 whole cell lysate Lane 3: HCT116 whole cell lysate Lane 4: Human high value serum Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 46 kDa Observed band size: 46 kDa . |
 | Immunofluorescent analysis of MCF-7 cells using PACO28838 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO28838 at dilution of 1:100. |
| Background: | Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1. |
| Synonyms: | Procollagen C-endopeptidase enhancer 2 (Procollagen COOH-terminal proteinase enhancer 2) (PCPE-2) (Procollagen C-proteinase enhancer 2), PCOLCE2, PCPE2 |
| UniProt Protein Function: | PCOLCE2: Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 3q21-q24Molecular Function: collagen binding; heparin binding; protease activator activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9UKZ9 |
| NCBI GenInfo Identifier: | 67470587 |
| NCBI Gene ID: | 26577 |
| NCBI Accession: | Q9UKZ9.1 |
| UniProt Secondary Accession: | Q9UKZ9,Q9BRH3, B2RCH9, D3DNG4 |
| UniProt Related Accession: | Q9UKZ9 |
| Molecular Weight: | 45,717 Da |
| NCBI Full Name: | Procollagen C-endopeptidase enhancer 2 |
| NCBI Synonym Full Names: | procollagen C-endopeptidase enhancer 2 |
| NCBI Official Symbol: | PCOLCE2 |
| NCBI Official Synonym Symbols: | PCPE2 |
| NCBI Protein Information: | procollagen C-endopeptidase enhancer 2; procollagen C-proteinase enhancer 2; procollagen COOH-terminal proteinase enhancer 2 |
| UniProt Protein Name: | Procollagen C-endopeptidase enhancer 2 |
| UniProt Synonym Protein Names: | Procollagen COOH-terminal proteinase enhancer 2 |
| Protein Family: | |
| UniProt Gene Name: | PCOLCE2 |
| UniProt Entry Name: | PCOC2_HUMAN |
| Antibodies |
| PCOLCE2 Antibody (PACO11112) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
