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PE Anti-Human CD134 Antibody [Ber-ACT35] (AGEL3269)

Datasheet MSDS
SKU AGEL3269
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, k
Clone Ber-ACT35
Conjugation PE
€82 - €325

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Description

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PE Anti-Human CD134 Antibody [Ber-ACT35]

The PE Anti-Human CD134 Antibody (BER-ACT35) available on www.assaygenie.com is a vital tool for researchers studying CD134, a cell surface molecule that plays a key role in immune activation and regulation. This antibody, produced for use in flow cytometry applications, specifically targets human samples with high specificity and sensitivity.CD134, also known as OX40, is a co-stimulatory molecule expressed on activated T cells and is involved in enhancing immune responses. Its interaction with its ligand is crucial for maintaining T cell activation and promoting inflammation, making it a significant target for studies in immunology and immune-related diseases.

Understanding the function and expression of CD134 is essential for exploring its role in diseases like cancer, infectious diseases, and autoimmune conditions.The PE Anti-Human CD134 Antibody (BER-ACT35) enables precise detection and analysis of CD134 expression on various cell types, providing valuable insights into immune responses and potential therapeutic interventions. Researchers can utilize this antibody to further dissect the role of CD134 in immune regulation and develop targeted treatments for various immune-related disorders.

Product Title:PE Anti-Human CD134 Antibody [Ber-ACT35]
SKU:AGEL3269
Size:20 Tests, 100 Tests, 200 Tests
Clone No:Ber-ACT35
Synonyms:TXGP1L;TNFRSF4;ACT35 antigen;OX40L receptor;CD134;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P43489
Gene ID:7293
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.
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