Description

PE Anti-Human CD40 Antibody [3A8]

The PE Anti-Human CD40 Antibody (3A8) from AssayGenie is a powerful tool for research involving CD40, a cell surface receptor with a key role in immune responses and inflammation. This antibody, conjugated with phycoerythrin (PE), offers high specificity and sensitivity for detecting CD40 expression in human samples. Validated for use in flow cytometry applications, the 3A8 antibody allows for precise analysis of CD40 levels on various cell types, aiding in studies related to immunology, cancer, and autoimmune diseases.CD40 is a crucial receptor involved in the activation of immune cells and the regulation of adaptive immune responses.

Its dysregulation has been linked to various diseases including cancer, autoimmune disorders, and infectious diseases. The PE Anti-Human CD40 Antibody (3A8) enables researchers to investigate the role of CD40 in these conditions and explore potential therapeutic strategies targeting this receptor.With its high specificity and reliable performance, the PE Anti-Human CD40 Antibody (3A8) is an essential tool for scientists seeking to delve into the intricate mechanisms of immune system modulation and inflammatory processes. Enhance your research endeavors with this cutting-edge antibody from AssayGenie.

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Product Title:	PE Anti-Human CD40 Antibody [3A8]
SKU:	AGEL2795
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	3A8
Synonyms:	Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG2a, κ
Isotype Control:	PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:	Liquid
Conjugation:	PE
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P25942
Gene ID:	958
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

PE Anti-Human CD40 Antibody [3A8] (AGEL2795)

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Description