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PE Anti-Mouse CD3ε Antibody [145-2C11] (AGEL2202)

Datasheet MSDS
SKU AGEL2202
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Armenian Hamster
Isotype Armenian Hamster IgG
Clone 145-2C11
Conjugation PE
$40 - $119

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Mouse CD3ε Antibody [145-2C11]

The PE Anti-Mouse CD3 Antibody (145-2C11) offered by Assay Genie is a highly specific and reliable tool for researchers studying mouse immune responses. This antibody is optimized for flow cytometry applications, enabling precise detection and analysis of CD3, a vital cell surface marker associated with T cell activation and function.The 145-2C11 antibody is validated for use in various mouse samples, providing researchers with a powerful tool for investigating T cell populations in immunology, infectious diseases, and autoimmune research. Its high sensitivity and specificity make it ideal for identifying and characterizing CD3-expressing cells in experimental models, offering insights into immune responses and diseases.

By targeting the CD3 protein, this antibody allows researchers to explore the dynamic interactions and functions of T cells, paving the way for advancements in immunotherapy, vaccine development, and understanding immune-related disorders. With its superior performance and versatility, the PE Anti-Mouse CD3 Antibody (145-2C11) is an essential tool for unraveling the complexities of the immune system and advancing scientific discoveries in the field of immunology.

Product Title:PE Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL2202
Size:25µg, 100µg
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
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