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PE/Cyanine5.5 Anti-Mouse CD8a Antibody [53-6.7] (AGEL2204)

Datasheet MSDS
SKU AGEL2204
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, κ
Clone 53-6.7
Conjugation PE/Cyanine5.5
$53 - $143

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine5.5 Anti-Mouse CD8a Antibody [53-6.7]

The PE-Cyanine5.5 Anti-Mouse CD8a Antibody (53-6.7) offered by AssayGenie is a high-quality reagent designed for precise detection and analysis of CD8a cell surface marker in mouse samples. This antibody, validated for flow cytometry applications, specifically targets CD8a, a crucial marker for cytotoxic T cells, aiding in the identification and characterization of these important immune cells in various experimental settings.CD8a is a key component of the immune system, playing a vital role in the recognition and elimination of infected or abnormal cells.

By targeting CD8a, researchers can gain insights into the activation and function of cytotoxic T cells, furthering our understanding of immune responses in diseases such as infections, cancer, and autoimmunity. The PE-Cyanine5.5 Anti-Mouse CD8a Antibody (53-6.7) is a valuable tool for immunology research, offering reliable and specific detection of CD8a to support a wide range of studies aimed at unraveling the complexities of the immune system.

Product Title:PE/Cyanine5.5 Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL2204
Size:50 Tests, 100 Tests, 200 Tests
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
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