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PE/Cyanine5.5 Anti-Mouse H-2 Antibody [M1/42] (AGEL2422)

Datasheet MSDS
SKU AGEL2422
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, κ
Clone M1/42
Conjugation PE/Cyanine5.5
€100 - €275

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine5.5 Anti-Mouse H-2 Antibody [M1/42]

The PE-Cyanine5.5 Anti-Mouse H-2 Antibody (M1/42) is a vital tool for researchers looking to study mouse immune responses. This antibody, designed for use in flow cytometry applications, specifically targets H-2 molecules on mouse cells. With its high specificity and sensitivity, it allows for accurate detection and analysis of H-2 expression in various cell populations.The H-2 molecules, major histocompatibility complex class I proteins, play a crucial role in antigen presentation and immune responses in mice. By using the PE-Cyanine5.5 Anti-Mouse H-2 Antibody, researchers can delve into the intricacies of immune recognition and activation in mouse models, shedding light on the mechanisms underlying immune-related diseases and therapeutic interventions.

Whether investigating immune responses in infectious diseases, autoimmune disorders, or vaccine development, this antibody provides a valuable tool for researchers aiming to understand the complexities of the mouse immune system. Its reliability and performance make it an indispensable asset for immunology and therapeutic research endeavors involving mouse models.

Product Title:PE/Cyanine5.5 Anti-Mouse H-2 Antibody [M1/42]
SKU:AGEL2422
Size:25µg, 100µg
Clone No:M1/42
Synonyms:Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:111364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.
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