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PerCP Anti-Mouse CD5 Antibody [53-7.3] (AGEL3377)

Datasheet MSDS
SKU AGEL3377
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, k
Clone 53-7.3
Conjugation PerCP
€100 - €300

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Description

system_update_altDatasheetsystem_update_altMSDS

PerCP Anti-Mouse CD5 Antibody [53-7.3]

The Mouse Anti-Mouse CD5 Antibody 53-7.3 (AGEL3377) is a vital tool for researchers studying the CD5 antigen, a cell surface glycoprotein expressed on T cells, B cells, and thymocytes that plays a key role in immune response regulation. This monoclonal antibody, specifically targeting mouse samples, is produced for applications such as flow cytometry and immunoprecipitation, allowing for precise detection and analysis of CD5 expression levels in various cell populations.CD5, a marker of T and B cell subsets, is involved in signaling pathways that modulate immune cell activation and tolerance.

Research on CD5 is invaluable for understanding pathways linked to autoimmunity, tolerance induction, and immune cell development. By targeting CD5 with the 53-7.3 Antibody, researchers can gain insights into the functions and mechanisms associated with this important antigen, contributing to advancements in immunology and potential therapeutic strategies for immune-related disorders.

Product Title:PerCP Anti-Mouse CD5 Antibody [53-7.3]
SKU:AGEL3377
Size:25µg, 100µg
Clone No:53-7.3
Synonyms:Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P13379
Gene ID:12507
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.
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