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PerCP/Cyanine5.5 Anti-Mouse CD54 Antibody [YN1/1.7.4] (AGEL3138)

Datasheet MSDS
SKU AGEL3138
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone YN1/1.7.4
Conjugation PerCP/Cyanine5.5
$53 - $143

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Description

system_update_altDatasheetsystem_update_altMSDS

PerCP/Cyanine5.5 Anti-Mouse CD54 Antibody [YN1/1.7.4]

The PERCP-Cyanine5.5 Anti-Mouse CD54 Antibody (YN1/1.7.4) offered by Assay Genie is a valuable tool for researchers interested in studying CD54 expression in mouse samples. This monoclonal antibody is specifically designed to target CD54, also known as intercellular adhesion molecule-1 (ICAM-1), a cell surface glycoprotein involved in immune response and cell adhesion processes.The YN1/1.7.4 antibody, optimized for use in flow cytometry applications, exhibits high specificity and sensitivity in detecting CD54 expression in mouse cells. Its precise binding properties facilitate the accurate identification and quantification of CD54-positive cells, making it an essential reagent for immunology, inflammation, and infection studies.

By targeting CD54, researchers can gain insights into the dynamics of immune cell interactions and inflammatory responses in various experimental models. The use of this antibody opens up possibilities for investigating the role of CD54 in immune cell adhesion, migration, and signaling pathways, ultimately contributing to a deeper understanding of immune system function and the development of targeted therapies for immune-related diseases.Assay Genie’s PERCP-Cyanine5.5 Anti-Mouse CD54 Antibody (YN1/1.7.4) provides a reliable and efficient solution for researchers seeking to explore the intricate mechanisms of immune regulation and cell communication mediated by CD54 in mouse models.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD54 Antibody [YN1/1.7.4]
SKU:AGEL3138
Size:50 Tests, 100 Tests, 200 Tests
Clone No:YN1/1.7.4
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P13597
Gene ID:15894
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
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