Description
Pig CD163 Recombinant Protein (N-His)
Pig CD163 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser577-Asn926, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Scavenger receptor cysteine-rich type 1 protein M130 is a ~120 kDa protein. Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. For research use only.
May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV).
| Product Name: | Pig CD163 Recombinant Protein (N-His) |
| SKU: | GXRP14102 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Pig |
| Synonyms: | CD163, M130, Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser577-Asn926 |
| UniProt: | Q2VL90 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
