POLQ Antibody (PACO03362)
- SKU:
- PACO03362
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | POLQ Antibody |
| Antibody SKU: | PACO03362 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the N-terminal region of human DNA pol Theta. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | POLQ; POLH; DNA polymerase theta; DNA polymerase eta |
| UniProt Protein Function: | POLQ: Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links. Belongs to the DNA polymerase type-A family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: DNA repair, damage; Transferase; EC 2.7.7.7Chromosomal Location of Human Ortholog: 3q13.33Cellular Component: nucleoplasmMolecular Function: DNA-directed DNA polymerase activity; damaged DNA binding; ATP binding; single-stranded DNA-dependent ATPase activityBiological Process: DNA repair; DNA-dependent DNA replication |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O75417 |
| NCBI GenInfo Identifier: | 139394648 |
| NCBI Gene ID: | 10721 |
| NCBI Accession: | NP_955452.3 |
| UniProt Secondary Accession: | O75417 |
| UniProt Related Accession: | O75417 |
| Molecular Weight: | Mol Weight: 289kDa, 150kD, 78kD (POLH) |
| NCBI Full Name: | DNA polymerase theta |
| NCBI Synonym Full Names: | DNA polymerase theta |
| NCBI Official Symbol: | POLQÂ Â |
| NCBI Official Synonym Symbols: | PRO0327Â Â |
| NCBI Protein Information: | DNA polymerase theta |
| UniProt Protein Name: | DNA polymerase theta |
| UniProt Synonym Protein Names: | DNA polymerase eta |
| Protein Family: | DNA polymerase |
| UniProt Gene Name: | POLQÂ Â |
| UniProt Entry Name: | DPOLQ_HUMAN |
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