The POLR1C Antibody (CAB0269) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, generated in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.POLR1C is a key component of the RNA polymerase I complex, essential for the synthesis of ribosomal RNA and protein translation. Dysregulation of POLR1C has been associated with various diseases, including cancer and developmental disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
POLR1C Antibody
SKU:
CAB0269
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
9533
RRID
AB_2757082
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using POLR1C Rabbit pAb (CAB0269) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
