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POU2F1/POU2F2 Antibody (PACO01196)

SKU:
PACO01196
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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Antibody Name:POU2F1/POU2F2 Antibody
Antibody SKU:PACO01196
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from human 41183 around the non-phosphorylation site of S385.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:POU2F1; OCT1; OTF1; POU domain; class 2, transcription factor 1; NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1; POU2F2; OCT2; OTF2; POU domain, class 2, transcription factor 2; Lymphoid-restricted im
UniProt Protein Function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
NCBI Summary:The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010]
UniProt Code:P14859
NCBI GenInfo Identifier:28202257
NCBI Gene ID:5451
NCBI Accession:P14859.2
UniProt Secondary Accession:P14859,Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1, B1AL91, B1AL93 B4E029, J3KP77,
UniProt Related Accession:P14859
Molecular Weight:72,082 Da
NCBI Full Name:POU domain, class 2, transcription factor 1
NCBI Synonym Full Names:POU class 2 homeobox 1
NCBI Official Symbol:POU2F1  
NCBI Official Synonym Symbols:OCT1; OTF1; oct-1B  
NCBI Protein Information:POU domain, class 2, transcription factor 1
UniProt Protein Name:POU domain, class 2, transcription factor 1
UniProt Synonym Protein Names:NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1
Protein Family:POU domain, class 2, transcription factor
UniProt Gene Name:POU2F1  
UniProt Entry Name:PO2F1_HUMAN

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