The PPIL6 Polyclonal Antibody (PAC011406) is a vital tool for researchers studying PPIL6, a peptidyl-prolyl cis-trans isomerase involved in protein folding and function. This antibody, generated in rabbits, exhibits high specificity for human samples and is optimized for use in Western blot applications. By binding to the PPIL6 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a valuable asset for studies in molecular biology and protein research.PPIL6, also known as Cyclophilin D, plays a crucial role in protein folding and the regulation of mitochondrial function, making it a key player in cellular physiology and metabolism.
Its functions in protein folding and disease pathogenesis make it a promising target for research into disorders such as neurodegenerative diseases, metabolic disorders, and cancer. By understanding the mechanisms of PPIL6, researchers can unravel its roles in disease progression and potentially develop therapeutic interventions targeting this protein.
PPIL6: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 5.2.1.8; IsomeraseChromosomal Location of Human Ortholog: 6q21Molecular Function: peptidyl-prolyl cis-trans isomerase activity