Pritoxaximab Antibody is a research-grade biosimilar monoclonal antibody targeting shiga toxin type 1stx1B. It is a chimeric IgG1-kappa antibody. Reactivity: Escherichia coli. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Shiga toxin subunit B (shiga toxin type 1Bstx1B) is a ~9 kDa protein. The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.