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Western blot analysis of extracts of T-47D cells, using Progesterone Receptor antibody (CAB22061) at 1:10000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Key Features

Progesterone Receptor Monoclonal Antibody (CAB22061)

Datasheet MSDS
SKU CAB22061
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Rabbit
Synonyms PR, NR3C3, Progesterone Receptor
€131 - €457

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Description

system_update_altDatasheetsystem_update_altMSDS

Progesterone Receptor Monoclonal Antibody (CAB22061)

The Progesterone Receptor Monoclonal Antibody (CAB22061) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, specifically designed for human samples, is highly sensitive and specific for detecting the progesterone receptor in Western blot applications.The progesterone receptor plays a key role in regulating the effects of progesterone, a hormone involved in reproductive functions, pregnancy, and other biological processes. Dysregulation of the progesterone receptor has been linked to conditions such as infertility, endometrial cancer, and breast cancer, making it a key target for research and therapeutic development.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:Progesterone Receptor Monoclonal Antibody
SKU:CAB22061
Size:20μL, 100μL
Reactivity:Human
Clone Number:ARC5121-01
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:5000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PR, NR3C3, Progesterone Receptor
Positive Sample:T-47D
Cellular Localization:Cytoplasm, Cytoplasm, Mitochondrion Outer Membrane, Nucleus.
Calculated MW:99kDa
Observed MW:90kDa(PR-A)/118kDa(PR-B)

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Purification MethodAffinity purification
Gene ID5241
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from T-47D cells, using Progesterone Receptor Rabbit mAb (CAB22061) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 4s.
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