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PRV-A NSP2 Recombinant Protein (C-His)
Key Features

PRV-A NSP2 Recombinant Protein (C-His) (GXRP10280)

SKU GXRP10280
Product Type Recombinant Protein
Species RV-A
Expression System E. coli
Tag C-His
$458 - $2,412

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Description

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PRV-A NSP2 Recombinant Protein (C-His)

PRV-A NSP2 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Ile317, with a C-terminal His tag. Predicted molecular weight: 37.45 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Non-structural protein 2 is a ~36 kDa protein. Participates in replication and packaging of the viral genome. For research use only.

Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities. The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures. The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.

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