PSG9 Antibody (PACO62023)
- SKU:
- PACO62023
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | PSG9 Antibody (PACO62023) |
| Antibody SKU: | PACO62023 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pregnancy-specific beta-1-glycoprotein 9 protein (241-426AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO62023 diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of MCF-7 cells with PACO62023 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | IHC image of PACO62023 diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | female pregnancy |
| Synonyms: | Pregnancy-specific beta-1-glycoprotein 9 (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9) (PS34) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (Pregnancy-specific beta-1-glycoprotein 11) (PS-beta-G-11) (PSBG-11) (Pregnancy-specific glycoprotein 11) (Pregnancy-specific glycoprotein 7) (PSG7), PSG9, PSG11 |
| UniProt Protein Function: | PSG9: Belongs to the immunoglobulin superfamily. CEA familyProtein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 19q13.2Biological Process: female pregnancy |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014] |
| UniProt Code: | Q00887 |
| NCBI GenInfo Identifier: | 6093845 |
| NCBI Gene ID: | 5678 |
| NCBI Accession: | Q00887.2 |
| UniProt Secondary Accession: | Q00887,Q15227, Q15236, Q15237, Q8WW78, Q9UQ73, B2R869 |
| UniProt Related Accession: | Q00887 |
| Molecular Weight: | 45,336 Da |
| NCBI Full Name: | Pregnancy-specific beta-1-glycoprotein 9 |
| NCBI Synonym Full Names: | pregnancy specific beta-1-glycoprotein 9 |
| NCBI Official Symbol: | PSG9Â Â |
| NCBI Official Synonym Symbols: | PS34; PSG11; PSGII; PSBG-9; PSBG-11Â Â |
| NCBI Protein Information: | pregnancy-specific beta-1-glycoprotein 9 |
| UniProt Protein Name: | Pregnancy-specific beta-1-glycoprotein 9 |
| UniProt Synonym Protein Names: | PS34; Pregnancy-specific beta-1 glycoprotein B; PS-beta-B; Pregnancy-specific beta-1-glycoprotein 11; PS-beta-G-11; PSBG-11; Pregnancy-specific glycoprotein 11; Pregnancy-specific glycoprotein 7; PSG7 |
| Protein Family: | Pregnancy-specific beta-1-glycoprotein |
| UniProt Gene Name: | PSG9Â Â |
| UniProt Entry Name: | PSG9_HUMAN |
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