The Purified Anti-Human CD11a Antibody (R7-1) available at www.assaygenie.com is a cutting-edge tool designed for researchers delving into the intricate realm of human immunology. Specifically targeted towards CD11a, a crucial cell surface protein involved in immune cell adhesion and signaling, this antibody offers a precise and reliable method for studying CD11a functions in various biological contexts.Derived with meticulous care, this antibody is purified to ensure high specificity and minimal background interference, making it an ideal choice for a wide range of experimental techniques. Whether used in Western blotting, immunohistochemistry, flow cytometry, or other applications, researchers can trust in the consistent performance and accuracy of the Anti-Human CD11a Antibody (R7-1).
The CD11a protein plays a pivotal role in immune cell interactions, such as T-cell activation and migration, making it a key target for research in immunology, inflammation, and autoimmune diseases. By utilizing this advanced antibody, scientists can uncover new insights into the mechanisms governing immune responses and potentially discover novel therapeutic strategies for conditions influenced by dysregulated immune function.In summary, the Purified Anti-Human CD11a Antibody (R7-1) from Assay Genie represents a powerful tool for unraveling the complexities of human immunology and advancing our understanding of CD11a-mediated processes in health and disease.
Product Title:
Purified Anti-Human CD11a Antibody [R7-1]
SKU:
AGEL2389
Size:
25µg, 100µg
Clone No:
R7-1
Synonyms:
Integrin alpha-L;LFA-1A;CD11A;ITGAL;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
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