Purified Anti-Human/Mouse IL-5 Antibody [TRFK5] (AGEL2382)
- SKU:
- AGEL2382
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- ICFCM
- ELISA
- Reactivity:
- Human
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG1, κ
- Clone:
- TRFK5
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Title: | Purified Anti-Human/Mouse IL-5 Antibody [TRFK5] |
SKU: | AGEL2382 |
Size: | 25µg, 100µg |
Clone No: | TRFK5 |
Synonyms: | Interleukin-5;IL-5;B-cell differentiation factor I;T-cell replacing factor;TRF; |
Host Species: | Rat |
Reactivity: | Human;Mouse |
Application: | ICFCM;ELISA |
Isotype: | Rat IgG1, κ |
Isotype Control: | Purified Rat IgG1, κ Isotype Control[HRPN] |
Form: | Liquid |
Conjugation: | Unconjugated |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | P05113 P04401 |
Gene ID: | 3567,16191 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5. |