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Purified Anti-Human/Mouse IL-5 Antibody [TRFK5] (AGEL2382)

Datasheet MSDS
SKU AGEL2382
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications ICFCM
Applications ELISA
Reactivity Human
Reactivity Mouse
Host Species Rat
Isotype Rat IgG1, κ
Clone TRFK5
Conjugation Unconjugated
$33 - $83

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Description

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Purified Anti-Human/Mouse IL-5 Antibody [TRFK5]

The Purified Anti-Human/Mouse IL-5 Antibody (TRFK5) is a powerful tool for researchers investigating interleukin-5 (IL-5), a cytokine involved in the immune system's response to infections and allergies. This antibody, produced using advanced purification techniques, is highly specific and binds selectively to IL-5 in both human and mouse samples. Validated for use in a variety of applications, including ELISA and immunohistochemistry, the TRFK5 antibody enables precise detection and analysis of IL-5 levels in different biological samples.IL-5 is a key regulator of eosinophil differentiation, activation, and survival, making it a critical mediator in allergic responses and asthma pathogenesis.

By targeting IL-5, researchers can gain insights into the mechanisms underlying these conditions and explore potential therapeutic interventions. The TRFK5 antibody provides a reliable tool for studying IL-5 in various research areas, including immunology, respiratory diseases, and inflammation-related disorders. Its high specificity and sensitivity make it an asset for elucidating the role of IL-5 in health and disease, driving important advancements in biomedical research.

Product Title:Purified Anti-Human/Mouse IL-5 Antibody [TRFK5]
SKU:AGEL2382
Size:25µg, 100µg
Clone No:TRFK5
Synonyms:Interleukin-5;IL-5;B-cell differentiation factor I;T-cell replacing factor;TRF;
Host Species:Rat
Reactivity:Human;Mouse
Application:ICFCM;ELISA
Isotype:Rat IgG1, κ
Isotype Control:Purified Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05113 P04401
Gene ID:3567,16191
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.
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