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Anti-PVALB Antibody (CAB13538)

SKU:
CAB13538
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 4 Anti-PVALB Antibody CAB13538
  • Cell Biology Antibodies 4 Anti-PVALB Antibody CAB13538
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-PVALB Antibody
Antibody SKU:CAB13538
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human PVALB (NP_002845.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse skeletal muscle, Rat skeletal muscle
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human PVALB (NP_002845.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSMT DLLN AEDI KKAV GAFS ATDS FDHK KFFQ MVGL KKKS ADDV KKVF HMLD KDKS GFIE EDEL GFIL KGFS PDAR DLSA KETK MLMA AGDK DGDG KIGV DEFS TLVA ES
Gene ID:5816
Uniprot:P20472
Cellular Location:
Calculated MW:12kDa
Observed MW:13kDa
Synonyms:D22S749, Parvalbumin, PVALB, parvalbumin
Background:The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:PVA: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: protein complex; cell soma; axon; cytoplasm; nucleus

Molecular Function:protein homodimerization activity; protein heterodimerization activity; calcium ion binding

Biological Process: cytosolic calcium ion homeostasis

NCBI Summary:The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. [provided by RefSeq, Jul 2008]
UniProt Code:P20472
NCBI GenInfo Identifier:131100
NCBI Gene ID:5816
NCBI Accession:P20472.2
UniProt Secondary Accession:P20472,P78378, Q4VB78, Q5R3Q9, B2R4H7,
UniProt Related Accession:P20472
Molecular Weight:110
NCBI Full Name:Parvalbumin alpha
NCBI Synonym Full Names:parvalbumin
NCBI Official Symbol:PVALB  
NCBI Official Synonym Symbols:D22S749  
NCBI Protein Information:parvalbumin alpha
UniProt Protein Name:Parvalbumin alpha
Protein Family:Parvalbumin
UniProt Gene Name:PVALB  
UniProt Entry Name:PRVA_HUMAN
Anti-PVALB Antibody (CAB13538)Western blot analysis of extracts of various cell lines, using PVALB antibody (CAB13538) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-PVALB Antibody (CAB13538)Immunohistochemistry of paraffin-embedded human esophageal using PVALB Rabbit pAb (CAB13538) at dilution of 1:100 (40x lens).

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