The RAB4A Antibody (CAB6712) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has high specificity and sensitivity for detecting Rab4A in human samples, making it an ideal choice for Western blot experiments.Rab4A is crucial for controlling the recycling of proteins from endosomes back to the cell surface, a process that is essential for maintaining cell function and homeostasis. Dysregulation of Rab4A has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic intervention.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
RAB4A Antibody
SKU:
CAB6712
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
RAB4, HRES1, HRES-1, HRES-1/RAB4, RAB4A
Positive Sample:
Neuro-2a, Mouse brain, Rat brain
Cellular Localization:
Cytoplasm, Membrane, Peripheral Membrane Protein.
Calculated MW:
24kDa
Observed MW:
25kDa
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.
Purification Method
Affinity purification
Gene ID
5867
RRID
AB_2767296
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using RAB4A Rabbit pAb (CAB6712) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
