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Rabbit IL1B/IL1F2 Recombinant Protein (C-His)
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Rabbit IL1B/IL1F2 Recombinant Protein (C-His) (GXRP12806)

SKU GXRP12806
Product Type Recombinant Protein
Species Rabbit
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Rabbit IL1B/IL1F2 Recombinant Protein (C-His)

Rabbit IL1B/IL1F2 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Ala117-Ser268, with a C-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interleukin-1 beta is a ~30 kDa protein. Potent pro-inflammatory cytokine. For research use only.

Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.

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