Description
RABV G/Glycoprotein Recombinant Protein (C-His)
RABV G/Glycoprotein Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Leu524, with a C-terminal His tag. Predicted molecular weight: 60 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 5 mM EDTA, 0.1% CHAPS, 4% Trehalose，1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. For research use only.
In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
| Product Name: | RABV G/Glycoprotein Recombinant Protein (C-His) |
| SKU: | GXRP03569 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | RABV |
| Synonyms: | G, Glycoprotein |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Leu524 |
| Calculated MW: | 60 kDa |
| UniProt: | P08667 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 5 mM EDTA, 0.1% CHAPS, 4% Trehalose，1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
