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Rat S100B Recombinant Protein (N-His)
Key Features

Rat S100B Recombinant Protein (N-His) (GXRP08178)

SKU GXRP08178
Product Type Recombinant Protein
Species Rat
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Rat S100B Recombinant Protein (N-His)

Rat S100B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Glu92, with an N-terminal His tag. Predicted molecular weight: 11.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein S100-B (S100B) is a ~10 kDa protein. Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain. For research use only.

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Acts as a neurotrophic factor that promotes astrocytosis and axonal proliferation. Involved in innervation of thermogenic adipose tissue by acting as an adipocyte-derived neurotrophic factor that promotes sympathetic innervation of adipose tissue.

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