The Recombinant 2B4/CD244 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C320069) against CD244. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of NK-92 and IHC analysis of Human tonsil. The target is localized to the cell membrane.
Product Name:
Recombinant 2B4/CD244 Monoclonal Antibody
SKU:
AGEL5388
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
2B4, C9.1, CD244, CD244 antigen, CD244 molecule, CD244 molecule natural killer cell receptor 2B4, CD244 natural killer cell receptor 2B4, F730046O15Rik, h2B, h2B4, Ly90, member 4, NAIL, Natural killer cell activation-inducing ligand, Natural killer cell receptor 2B, Natural killer cell receptor 2B4, NK cell activation inducing ligand, NK cell activation inducing ligand NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B, NKR2B4, Nmrk, Non-MHC restricted killing associated, OTTHUMP00000027884, p38, signaling lymphocytic activation molecule 4, SLAM family, SLAM family member, SLAM family member 4, SLAMF, SLAMF4
Reactivity:
Human
Immunogen:
Recombinant Human 2B4 / CD244 protein
Applications:
WBIHC-P
Clonality:
Recombinant Monoclonal
Clone No:
C320069
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CD244
Conjugation:
Unconjugated
Observed MW:
70-120 kDa
Calculated MW:
42 kDa
Recommended Dilution:
WB 1:1000; IHC-P: 1:50
UniProt:
Q9BZW8
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
0.2 µm filtered solution in PBS
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.